Variability of laser-evoked potentials: attention, arousal and lateralized differences

Variability of laser-evoked potentials: attention, arousal and lateralized differences.

We recorded laser-evoked potentials (LEPs) from 20 normal subjects by stimulating the skin with pulses from an infrared CO2 laser. The conduction velocity of the peripheral afferent fibers mediating the LEPs averaged 14.9 m/sec. The amplitude of the LEP components correlated significantly with perceived stimulus intensity. During repetitive constant intensity stimulation, the peak-to-peak LEP a...

Laser-evoked potentials: normative values.

OBJECTIVE Laser-evoked potentials (LEPs) currently represent the most reliable and widely agreed method of investigating the A delta-fibre pathways. Many studies dealt with the usefulness of LEPs in peripheral and central nervous system diseases. We aimed at gaining normative values for LEP data. METHODS Using a CO2 laser stimulator we recorded LEPs after face, hand, and foot stimulation in 1...

Vigilance, attention, expectation and cortical evoked potentials.

Clinical usefulness of laser evoked potentials.

Several papers were published since the first clinical applications of laser evoked potentials (LEPs) in disorders of the nociceptive system. While studies produced until five years ago were mostly addressed at identifying lesions of the nociceptive system, more recent papers used LEPs as an instrumental tool for the diagnosis of neuropathic pain. LEPs have also proved useful in demonstrating t...

Somatosensory spatial attention modulates amplitudes, latencies, and latency jitter of laser-evoked brain potentials.

Several studies provided evidence that the amplitudes of laser-evoked potentials (LEPs) are modulated by attention. However, previous reports were based on across-trial averaging of LEP responses at the expense of losing information about intertrial variability related to attentional modulation. The aim of this study was to investigate the effects of somatosensory spatial attention on single-tr...